CRISPR technologies beyond genome editing and gene regulation
The genomes of various organisms encode a series of messages and instructions within their DNA sequences. Genome editing involves changing those sequences, thereby changing the messages. This can be done by inserting a cut or break in the DNA and tricking a cell's natural DNA repair mechanisms into introducing the changes one wants. CRISPR-Cas9 provides a means to do so.
In 2012, two pivotal research papers were published in the journals Science and PNAS, which helped transform bacterial CRISPR-Cas9 into a simple, programmable genome-editing tool.
The studies, conducted by separate groups, concluded that Cas9 could be directed to cut any region of DNA. This could be done by simply changing the nucleotide sequence of crRNA, which binds to a complementary DNA target. In the 2012 Science article, Martin Jinek and colleagues further simplified the system by fusing crRNA and tracrRNA to create a single "guide RNA." Thus, genome editing requires only two components: a guide RNA and the Cas9 protein
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- Regenerative Rehabilitation - Tissue Engineering 2019 (Netherlands)
- Regenerative Rehabilitation - Tissue Science Congress 2019 (Japan)
- Regenerative Therapy & stem cell therapy - Tissue Repair 2019 (Finland)
- Regulatory and Reimbursement Issues - Stem Cell Conference - 2019 (USA)
- Regulatory and Safety Aspects of Cell and Gene Therapy - Cell Therapy 2019 (Italy)
- Rejuvenation - Regenerative Medicine 2019 (Spain)
- Scaffolds - Stem Cell Congress 2019 (France)
- Scaffolds - Regenerative Medicine 2019 (Spain)
- Scaffolds - Tissue Engineering 2019 (Netherlands)
- Scaffolds and Matrix for Tissue regeneration - Tissue Science Congress 2019 (Japan)
- Scaffolds and Matrix for Tissue regeneration - Bio Banking 2019 (Canada)
- Scaffolds and Tissue Regeneration - Stem Regenerative 2019 (Finland)
- Semantics & Interoperability - Human Genome 2019 (UAE)
- Senescence Cells - Stem Cell Congress 2019 (France)
- Sickle Cell Anemia - Human Genetics Meet 2019 (UAE)
- Single Cell biology - Cell Biology 2019 (Finland)
- Stem Cell Market World Wide - Stem Cell Conference - 2019 (USA)
- Stem Cell and Regenerative Medicine - Tissue Engineering 2019 (Netherlands)
- Stem Cell Apoptosis and Signal Transduction - Stem Regenerative 2019 (Finland)
- Stem Cell Apoptosis and Signal Transduction - Stem Cell Conference - 2019 (USA)
- Stem Cell Biobanking - Bio Banking 2019 (Canada)
- Stem Cell Biology - Genomics 2019 (Germany)
- Stem Cell Biology - Stem Cell Congress 2019 (France)
- Stem Cell Biology and Epigenetics - Stem Regenerative 2019 (Finland)
- Stem Cell Biomarkers - Stem Cell Conference - 2019 (USA)
- Stem Cell Biotechnology - Stem Cell Congress 2019 (France)
- Stem Cell Biotechnology - Biotechnology 2019 (Germany)
- Stem Cell Biotechnology and Regenerative Medicine - Euro Biotechnology 2019 (Switzerland)
- Stem Cell Embryology - Stem Cell Conference - 2019 (USA)
- Stem Cell Engineering (SCE) - Regenerative Medicine 2019 (Spain)
- Stem Cell Epigenetics - Stem Cell Conference - 2019 (USA)
- Stem Cell Niche - Stem Cell Congress 2019 (France)
- Stem Cell Niches - Stem Regenerative 2019 (Finland)
- Stem Cell Niches & Bio banking - Stem Cell Conference - 2019 (USA)
- Stem Cell Technologies - Stem Cell Congress 2019 (France)
- Stem Cell Therapies - Cell Therapy 2019 (Italy)
- Stem Cell Therapies - Stem Cell Conference - 2019 (USA)
- Stem Cell Therapy - Stem Cell Congress 2019 (France)
- Stem Cell Therapy - Human Genetics Meet 2019 (UAE)
- Stem Cell Transplantation - Stem Cell Congress 2019 (France)
- Stem Cell Transplantation and Biomaterials - Stem Regenerative 2019 (Finland)
- Stem cell treatment for Diabetes - Regenerative Medicine 2019 (Spain)
- Stem Cells & Tissue Engineering - Cell Biology 2019 (Finland)
- Stem Cells & Types - Stem Cell Conference - 2019 (USA)
- Stem cells and Epigenetics - Epitranscriptomics 2019 (Finland)
- Stem Cells and its Applications - Cell Tissue Science 2019 (Singapore)
- Stem Cells and Regenerative Medicine - Biotech Asia Pacific 2019 (Japan)
- Stem Cells and Veterinary Applications - Stem Cell Conference - 2019 (USA)
- Stem Cells technology - Stem Cell Conference - 2019 (USA)
- Stem cells to Battle cancer - Regenerative Medicine 2019 (Spain)
- Stem Cells: Culture, Differentiation and Transplantation - Tissue Science Congress 2019 (Japan)
- Stem Cells: Culture, Differentiation and Transplantation - Bio Banking 2019 (Canada)
- Structural & Functional Genomics - Cell Biology 2019 (Finland)
- Structural Biology - Genomics 2019 (Germany)
- Structural Biology - Cell Biology 2019 (Finland)
- Structural Biology and Bioinformatics - CRISPR 2019 (USA)
- Synthetic Biology - Synthetic Biomaterials 2019 (UK)
- Synthetic Biotechnology - Synthetic Biomaterials 2019 (UK)
- Systemic Biology - Synthetic Biomaterials 2019 (UK)
- Systems and Synthetic Biotechnology - Biotechnology 2019 (Germany)
- Thalassemia - Human Genetics Meet 2019 (UAE)
- The Banking Process - Bio Banking 2019 (Canada)
- Therapeutic Genome Editing - CRISPR 2019 (USA)
- Therapeutic Metabolomics - Metabolomics Meeting 2019 (USA)
- Tissue Culture & Preservation - Tissue Science Congress 2019 (Japan)
- Tissue culture and Preservation - Tissue Repair 2019 (Finland)
- Tissue Culture and Preservation - Cell Tissue Science 2019 (Singapore)
- Tissue Engineering - Tissue Engineering 2019 (Netherlands)
- Tissue Engineering - Tissue Science Congress 2019 (Japan)
- Tissue Engineering - Biotech Asia Pacific 2019 (Japan)
- Tissue Engineering & Bioengineering - Tissue Repair 2019 (Finland)
- Tissue Engineering and 3D Printing - Regenerative Medicine 2019 (Spain)
- Tissue Engineering And Regenerative Medicine - Synthetic Biomaterials 2019 (UK)
- Tissue Engineering and Regenerative Medicine - Stem Cell Conference - 2019 (USA)
- Tissue Preservation and Bio Banking - Stem Cell Congress 2019 (France)
- Tissue Regeneration - Bio Banking 2019 (Canada)
- Tissue Regeneration - Regenerative Medicine 2019 (Spain)
- Tissue Regeneration - Tissue Engineering 2019 (Netherlands)
- Tissue Regeneration and Nanotechnology - Tissue Science Congress 2019 (Japan)
- Tissue Repair and Regeneration - Cell Tissue Science 2019 (Singapore)
- Tissue Repair and Regeneration - Tissue Repair 2019 (Finland)
- Tissue Science & Regenerative Medicine - Cell Therapy 2019 (Italy)
- Tissue Science and Engineering - Cell Tissue Science 2019 (Singapore)
- Toxicoepigenetics - Epigenetics 2019 (Austria)
- Toxicoepigenetics - Epigenetics 2019 (Austria)
- Track 10: Organ Engineering - Regenerative Medicine 2019 (Canada)
- Track 11: Bone and Cartilage Tissue Engineering - Regenerative Medicine 2019 (Canada)
- Track 12: Tissue Repair and Regeneration - Regenerative Medicine 2019 (Canada)
- Track 13: Bio materials in Regenerative Medicine - Regenerative Medicine 2019 (Canada)
- Track 14: Bio Imaging & Bio printing Tissues and Organs - Regenerative Medicine 2019 (Canada)
- Track 15: Stem cells - Regenerative Medicine 2019 (Canada)
- Track 16: Applications of Tissue Engineering - Regenerative Medicine 2019 (Canada)
- Track 1: Tissue Engineering - Regenerative Medicine 2019 (Canada)
- Track 2: Tissue Culture & Preservation - Regenerative Medicine 2019 (Canada)
- Track 3: Tissue Regeneration using Nanotechnology - Regenerative Medicine 2019 (Canada)
- Track 4: Regenerative Medicine - Regenerative Medicine 2019 (Canada)
- Track 5: Regenerative Treatment Models - Regenerative Medicine 2019 (Canada)
- Track 6: Cell Therapy - Regenerative Medicine 2019 (Canada)
- Track 7: Biomedical Engineering Techniques - Regenerative Medicine 2019 (Canada)
- Track 8: Bio materials - Regenerative Medicine 2019 (Canada)
- Track 9: Bio fabrication & 3 D-Bio printing in Life Sciences - Regenerative Medicine 2019 (Canada)
- Transcriptomics - Metabolomics Meeting 2019 (USA)
- Transgenerational Epigenetics Inheritance - Epigenetics Congress 2019 (South Africa)
- Translational & Regenerative Medicine - Tissue Repair 2019 (Finland)
- Translational Epigenetics - Epitranscriptomics 2019 (Finland)
- Translational Medicine - Cell Tissue Science 2019 (Singapore)
- Translational Stem cell research - Tissue Repair 2019 (Finland)
- Treatment of Genetic Disorders - Personalized Medicine 2019 (Canada)
- Tumour cell science - Stem Cell Conference - 2019 (USA)
- Umbilical cord blood and tissue-based therapies - Bio Banking 2019 (Canada)
- Viral Gene Therapies - Stem Regenerative 2019 (Finland)
- Viral Gene Therapy - Cell Therapy 2019 (Italy)
- Vitrification - Cell Tissue Science 2019 (Singapore)
- Whole Organ Engineering and Approaches - Regenerative Medicine 2019 (Spain)
- Xenobiotics - Metabolomics Meeting 2019 (USA)
- Yeast artificial Chromosome - Cell Biology 2019 (Finland)